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Top 10 Most Dangerous Highways/Trucker Routes in the U.S.

Updated: Mar 28

Navigating the highways of America as a trucker comes with its challenges, and some roads are notorious for being especially dangerous. Whether due to congestion, poor road conditions, or extreme weather, these highways present unique risks for truck drivers. Here’s a countdown of the top ten worst highways for truckers, ranked from bad to worst.

Aerial view of a complex highway interchange with multiple overlapping roads. Green spaces and patterns are visible between lanes.
An intricate network of winding highway on-off ramps creates a complex yet organized maze of elevated roadways.

10. Interstate 26 (I-26) – North Carolina & South Carolina

Known for steep grades and unpredictable weather in the mountains of North Carolina, I-26 can be treacherous, especially in winter.


9. Interstate 70 (I-70) – Colorado

With winding mountain passes and extreme snowfall, I-70 is a challenge for truckers, particularly over the Eisenhower Tunnel and Vail Pass.


8. Interstate 45 (I-45) – Texas

I-45, especially in the Houston area, is one of the deadliest highways in the U.S. due to heavy congestion and reckless driving.


7. Interstate 10 (I-10) – Louisiana & Texas

Bridges, flooding, and high accident rates make I-10 through Louisiana and Texas a major concern for truckers.


6. Interstate 285 (I-285) – Georgia

Atlanta’s bypass is infamous for high speeds, frequent wrecks, and heavy commercial traffic, making it a dangerous stretch for truckers.


5. Interstate 75 (I-75) – Florida & Georgia

Accidents are common on I-75, especially in Florida’s fog-prone and high-traffic areas, posing significant risks to truckers.


4. US Route 17 (US-17) – South Carolina & Florida

This highway’s poor lighting, sudden turns, and high accident rate make it a challenging route for truckers.


3. Interstate 95 (I-95) – East Coast

Stretching from Florida to Maine, I-95 is infamous for aggressive drivers, congestion, and frequent crashes.


2. US Route 285 (US-285) – New Mexico & Texas

Known as the "Death Highway," this route sees numerous fatal crashes, particularly due to oilfield traffic.


1. Interstate 80 (I-80) – Wyoming

Ranking as the worst for truckers, I-80 in Wyoming is notorious for blizzards, high winds, and black ice, leading to frequent pileups and closures.


Truckers face immense risks on these highways, making preparation and caution essential. Avoiding dangerous highways and trucker routes when possible and staying informed about weather and traffic conditions can help ensure a safer journey.


Got one to include in the list? Tell us which highways make your top 10 worst!


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